Following the rapid development of technology, the role of humans in production processes is changing – gradually routine tasks are delegated to artificial intelligence (AI). According to the forecast of the World Economic Forum, by 2025, 50% of workers will be forced to retrain due to the increasing role of new technologies in production activities. The increasing impact of technological innovations on the labor market and the potential risks due to robotization and automation of production are in the spotlight of the new issue of trendletters, produced as part of a joint project of the Human Capital Multidisciplinary Research Center and the UNESCO Futures Studies Chair (UNESCO Futures Literacy Chairs network).